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In a world that's changing really quickly, the only strategy that is guaranteed to fail is not taking risks.

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The question isn't 'What do we want to know about people?' It's, 'What do people want to tell about themselves?

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A squirrel dying in your front yard may be more relevant to your interests right now than people dying in Africa.

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Move fast and break things. Unless you are breaking stuff, you are not moving fast enough

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This is a perverse thing, personally, but I would rather be in the cycle where people are underestimating us. It gives us the latitude to go out and make big bets that excite and amaze people.

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People can be really smart or have skills that are directly applicable, but if they don't really believe in it, then they are not going to really work hard.

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The question I ask myself like almost every day is, 'Am I doing the most important thing I could be doing?' ... Unless I feel like I'm working on the most important problem that I can help with, then I'm not going to feel good about how I'm spending my time

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If you actually do something you love it's a lot easier and takes on a lot more purpose.